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The focal points of the show are the love triangle formed by series' protagonist Elena Gilbert (Dobrev) and vampire brothers Stefan Salvatore (Wesley) and Damon Salvatore (Somerhalder) and the town's supernatural history, involving Elena's friends and relatives.
At the end of season one, Elena meets her birth mother, Isobel, who is now a vampire, and she discovers that her uncle John, who she grew up hating, is her natural father.
In season two, she learns that she is a Petrova doppelgänger, resembling exactly Katherine Pierce, which means that she can be sacrificed to release Klaus' werewolf side.
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He also told her that he is the person that saved her the night of her parent's death.
She has a younger adoptive brother named Jeremy Gilbert, who is later revealed to be her biological cousin.
She also has an adoptive aunt named Jenna Sommers who serves as her and Jeremy's legal guardian in the first two seasons of the series.
After Stefan and Elena sleep together, she finds a picture of a woman named Katherine Pierce who looks exactly like her.
Stefan reveals that it is the women who made him and Damon feud 145 years ago, and the person who turned them into vampires.